Closed-loop Control of Anesthesia: Controlled Delivery of Remifentanil and Propofol


This pilot study will help us to collect information during anesthesia to improve the way the computer adjusts the level of anesthesia in adults. This study will provide important information about the safe use of remifentanil and propofol when using a computer to control anesthesia.

Who can participate in this study?

  • In order to participate in the study, you are 19 years of age or older and will be having an elective surgical procedure under general anesthesia in the operating room at Royal Columbian Hospital, New Westminster.

Who should not participate in this study?

  • You cannot participate if you are taking long term opioid analgesics (morphine-like drugs) or other sedative medications or have an allergy to either remifentanil or propofol (includes allergies to eggs, egg products, soybeans or soy products), or hypersensitivity to narcotic medications like remifentanil, or have a known or suspected neurological (brain) disease, or have a known abnormality in any previous EEG examination, or are unable to provide informed consent, or are currently enrolled in any other research study involving drugs or devices.


  • Actively recruting subjects.

For more information, please see the Consent/Information form or