The effects of dexmedetomidine on the heart beat and blood sugar during elective surgery in children


Dexmedetomidine is a sedative drug that is comonly used to improve calmness and reduce pain in children waking up after surgery. Some of the side effects of dexmedetomidine, such as a potential change in how the heart muscles contracts and changes in blood sugar, are poorly understood. The current study aims to examine these changes directly in healthy children undergoing elective surgery by measuring the heart beats (with an electrocardiogram) and blood sugar at specific times before and after dexmedetomidine is given. The investigators aim to establish a better understanding of this drug's safety profile.

Who can participate in this study?

  • In order to participate in the study, your child must be between 3 and 10 years old, having elective surgery and your anesthesiologist thinks that giving dexmedetomidine is appropriate.

Who should not participate in this study?

  • Your child cannot participate if they have heart disease or are on medication for their heart. Your child will not be asked to participate if they are allergic to dexmedetomidine or are not otherwise healthy.


  • Will begin recruiting in early 2015

For more information, please see the Consent/Information form or